cornell university cancer research

John Scott, PhD As the sole land-grant Ivy League university with both a rural and an urban footprint, Cornell and the Society for the Humanities occupy a unique position geographically and historically to address this pressing issue with the emerging tools of public and engaged humanities. The Ithaca Voice, Cornell Cancer Researchers Listen To Patients' Stories The Comparative Cancer Biology Program at Cornell University is a new initiative supported by the College of Veterinary Medicine to establish comprehensive interdisciplinary training and facilitate rigorous hypothesis-driven research in comparative cancer biology. Bob Riter-Cancer 101, Wed., February 6, 5:15-6:30pm, Vet School, Classroom 6 Wnt and the Immune System in Canine Osteosarcoma, Monday, April 15, 11am, Weill Hall 226 February 2016, Cancer Research at Cornell highlighted in SCOPES. It is one of the worlds leading archives of social science data, specializing in public opinion surveys from the 1930s to today. The Bronfenbrenner Center for Translational Research (BCTR) in the College of Human Ecology furthers research in the social and behavioral sciences, bridging the gap between research and outreach. For questions or comments about this website, please e-mail ec443@cornell.edu. SCACVIM Movie Screening Graduate Researcher. Cornell graduate students develop and contribute to transformative research projects that connect with local communities and have global benefits. Demystifying Chimeric Antigen Rececptor T Cell (CAR-T) therapy, Wed., March 13, 5:15-6:30pm, Vet School, Classroom 6 Joshua Swamidass, MD PhD The humanities are disciplines focused on critical engagement with society and culture, representations of global experience in art and literature, constructions of meaning across space and time, and the demands of ethics and truth. SCHIMENTI LAB | The talk, entitled, The National Cancer Institute: Leading Cancer Research in 2021 and Beyond, is available to watch here. An interdisciplinary collaboration used a materials science approach to "fingerprint" calcium mineral deposits that reveal pathological clues to the progression of breast cancer and potentially other diseases. Cancer Cell. I have keen interests in machine learning methods in radiation oncology, radiomics, and stereotactic ablative radiation therapies and hypo-fractionation. For more information, see the Education page. The BCTR recently received a $2.8 million grant from the United States Department of Health and Human Services to establish the Center for Creating Trauma-Informed Residential Settings through the Residential Child Care Projecta longtime program of the Bronfenbrenner Center. This project leads to the most comprehensive database in the world for survey questions related to health. WEISS LAB AND COLLABORATORS | WCM_Iadecola_BMRI_Milestones_2018_008.jpg. Cornell Chronicle, Cornell faculty featured in JAMA article on canine clinical trials for new cancer therapies, Tuesday, February 12, 4pm, Vet Research Tower LH3 Ankur Singh, an Associate Professor of George W. Woodruff School of Mechanical Engineering at Georgia Institute of Technology and Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University, has been awarded a five-year, $2.3 million RO1 grant from the National Cancer Institute of the National Institutes of Health (NIH) as PI. CARs and cTCRs: Design and Manufacture for Canine and Feline Cancers Exploring and Exploiting the SpatialConstraints of Cell Signaling, Tuesday, March 26, 4pm, Vet Research Tower LH3 For questions or comments about this website, please e-mail cct48@cornell.edu. The center also furthers the education of graduate students, medical students, fellow and postdoctoral trainees through several specialized programs in specific types of cancer, radiology and pathology. BMC Vet Res. Cornell Center on the Physics of Cancer Metabolism, Feil Family Brain and Mind Research Institute (BMRI), Bronfenbrenner Center for Translational Research, American Indian and Indigenous Studies Program, 2021 Research Stats & Faculty Distinctions, 2021Research Stats & Faculty Distinctions, Cornell's Research Leadership and Contacts. September 2016, HUS1 regulates in vivo responses to genotoxic chemotherapies. WEISS LAB AND COLLABORATORS | play Student Videos Insights on Drivers, Variant Calls, and Cancer Vaccines, Monday, April 15, 4pm, Schurman Hall LH1 April 2016, A SIRT2-Selective Inhibitor Promotes c-Myc Oncoprotein Degradation and Exhibits Broad Anticancer Activity. CARs and cTCRs: Design and Manufacture for Canine and Feline Cancers Class overview and introductory lecture Cornell, EDF aim to reduce methane output for Indias dairies, CNF jump-starts startups in New York state, Twitter Has Become the Modern-Day Colosseum, Electrochemistry converts carbon to useful molecules, Personal sensing at work: tracking burnout, balancing privacy, Codeswitching considered professional, study finds, Migrations initiative wins $5M Mellon grant for racial justice, New test offers clarity for couples struggling to conceive, New genomic tools help improve staple crops worldwide. Session Leader: Poppy McLeod, PhD; Cornell It teaches the acumen for solving some of life's greatest mysteries. Oncogene. The Comparative Cancer Biology Program at Cornell University is a new initiative supported by the College of Veterinary Medicine to establish comprehensive interdisciplinary training and facilitate rigorous hypothesis-driven research in comparative cancer biology. Research. T2006 Veterinary Research Tower, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853-6401. canceratcornelltrainees-l-request@cornell.edu. The long-term goal of the Comparative Cancer Program is to drive discovery throughout Cornell University toward advancement of new methods for prevention, diagnosis and therapeutic intervention of cancer. Thyroid Cancer, Wed., February 27, 5:15-6:30pm, Vet School, Classroom 6 Group communication and decision making, Wed., April 10, 5:15-6:30pm, Vet School, Classroom 6 The center supports basic science research programs in cancer biology and cancer genetics, translational research and clinical trials, and several collaborative research initiatives. Mina Bissell, PhD Los Angeles. Special Seminar - Center for Reproductive Genomics The thing thats so exciting about this grant is that it shows what a research leader the Residential Child Care Project is,and it provides them with an even larger platform for showing practitioners what the best research indicates and generating even more excellent research.. Genetics. Doris Johns Cherry Professor of Biology, Co-director, Rochester Aging Research Center Differences in Animal Biology Can Affect Cancer Drug Development, Weill Cornell Medicine Awarded NCI Grant For EBV-Related Lymphoma Research, Cancer Research Teams Awarded Grants from Starr Cancer Consortium, DNA Methylation Classifiers in the CNS and Beyond and Stopping the Bleed: Management of Post-partum Hemorrhage, The Mechanism of CaMKII Regulation: From Fertilization to Encoding Long-term Memory, "Mechanisms of Neuronal Polarity: Cytoskeleton Remodeling and Cargo Sorting", Leveraging C. Elegans Genetics To Understand Membrane-associated Machinery. BMS Seminar Series This all serves the centers ultimate goalto improve the care and clinical prognosis of breast cancer patients. They work in multidisciplinary teams that focus on translational research targeting individual cancers, as well as those focused on basic research that crosses multiple diseases across the cancer continuum. Joshua Swamidass, MD PhD Insights on Drivers, Variant Calls, and Cancer Vaccines, Monday, April 15, 4pm, Schurman Hall LH1 Cornell University is a private research university that provides an exceptional education for undergraduates and graduate and professional students. Cornell University Biology Publications & Citations Other Cornell University pages The Residential Child Care Project has long been recognized as a leader in terms of developing techniques that keep our most vulnerable childrenand those who care for themsafe and in showing how these techniques work in the real world, says Christopher Wildeman, Policy Analysis and Management, and director of the BCTR. When breath becomes air by Paul Kalanithi, Read the latest blogs on cancer biology written by Cornell Trainees, Cancer Resource Center of the Finger Lakes Collaborates with Cornell University Cornell Chronicle, Cornell faculty featured in JAMA article on canine clinical trials for new cancer therapies, Tuesday, February 12, 4pm, Vet Research Tower LH3 Interventions to Improve Healthspan and Lifespan: Lessons From Long-lived Mammals, Tuesday, March 5, 4pm, Schurman Hall LH4 The program brings together clinical and basic scientists at the College of . Cornell's colleges and schools encompass more than 100 fields of study, with locations in Ithaca, New York, New York City and Doha, Qatar. We are part of Cornell University (Ithaca, NY) but Weill Cornell Medical College is located in New York City. HUS1 regulates in vivo responses to genotoxic chemotherapies. Four interdisciplinary teams of physicians and scientists from Weill Cornell Medicine have been announced as recipients of the Sandra and Edward Meyer Cancer Center's inaugural Collaborative Research Initiative pilot project grants. The mission of Rural Humanities is to revisit the urban-rural dynamic, which has re-emerged as one of the most contested dividing lines today, and to critically approach, learn from, and make visible contemporary rural America, particularly in central-western New York. Why Don't We Get More Cancer? Learn More < > Research, creative experiences, and service learning are hallmarks of a Cornell undergraduate education. Department of Biology, University of Rochester OUR RESEARCH PROGRAMS Cancer Biology Cancer Genetics and Epigenetics Experimental Therapeutics Cancer Prevention and Control RESEARCH HIGHLIGHT It is supported by media polling units and research organizations that donate their data. The Cancer and Glioma Stem Cell Biology Laboratory, part of the Weill Cornell Brain Tumor Center and Meyer Cancer Center, is a highly interactive, translational research laboratory dedicated to . Department of Biology, University of Rochester RICHARDS LAB AND COLLABORATORS | University of Washington, School of Medicine 2011 Comparative Cancer Biology Program. The Roper Center maintains the worlds largest archive of survey data, including over 700,000 survey questions of samples from the United States and more than 23,000 datasets from over 100 countries. Student presentations and lab tours, Wed., April 17, 5:15-6:30pm, Vet School, Classroom 6 HUS1 regulates in vivo responses to genotoxic chemotherapies. Special Seminar - Center for Reproductive Genomics Dominic Boyer, Brent Hayes Edwards, Cymene Howe, and Kathi WeeksInvited Society Scholars for 20192020join the Societys faculty, graduate, and postdoctoral fellows. BMS Seminar Series Cornell Chronicle, Comparative Cancer Biology Training Program Awarded Cornell University Town-gown Award For Collaboration with the Cancer Resource Center of the Finger Lakes Undergraduate Research at Cornell University Home Imagine Research can lead you to become a student for life. T2006 Veterinary Research Tower, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853-6401. Washington University School of Medicine Dr.Yariv Houvras, right, with Dr. Ritu Kumar, an assistant professor of cell and developmental biology in surgery. Researchers discover that Australias superb lyrebird males imitate the panicked alarm calls of a mixed-species flock of birds while they are courting and even while mating with a female. Research at the Feil BMRI uses state-of-the-art tools to probe different facets of brain structure and function, from synaptic transmission to network activity, physiology of neural systems, and behavioral function. SCHIMENTI LAB | Companion Animal Hospital in Ithaca, NY for cats, dogs, exotics, and wildlife, Equine and Nemo Farm Animal Hospitals in Ithaca, NY for horses and farm animals, Cornell Ruffian Equine Specialists, on Long Island for every horse, Ambulatory and Production Medicine for service on farms within 30 miles of Ithaca, NY, Animal Health Diagnostic Center New York State Veterinary Diagnostic Laboratory, Cornell University College of Veterinary Medicine Ithaca, New York 14853-6401. Associate Professor of Pediatrics, Molecular Biology and Internal Medicine In addition to the CTNU, an integral part of the translational mission of the Feil BMRI are three institutes and centers: the Helen and Robert Appel Alzheimers Disease Research Institute, the Judith Jaffe Multiple Sclerosis Center, and the Center for Neurogenetics. Partnership between the Comparative Cancer Biology Program and the Cancer Resource Center of the Finger Lakes, Graduate Certificate of Engagement in Public Communication of Science and Technology. Millions of dollars of funding go into our labs every year. March 2016, Comprehensive genomic characterization of five canine lymphoid tumor cell lines. Integrating the engineering and physical sciences strengths available in Ithaca with those of the Meyer Cancer Center at Weill Cornell Medicine in New York City will be critical to ultimately translate these insights into improved therapies.. Companion Animal Hospital in Ithaca, NY for cats, dogs, exotics, and wildlife, Equine and Nemo Farm Animal Hospitals in Ithaca, NY for horses and farm animals, Cornell Ruffian Equine Specialists, on Long Island for every horse, Ambulatory and Production Medicine for service on farms within 30 miles of Ithaca, NY, Animal Health Diagnostic Center New York State Veterinary Diagnostic Laboratory, Cornell University College of Veterinary Medicine Ithaca, New York 14853-6401, Dr. Norman Sharpless, director of the National Cancer Institute at the NIH, gavethe Distinguished Lecture in Cancer Biology on Sept. 24, 2021. Nicolas Buchon Host/microbe relationships and control of intestinal stem . The grants will fund research on the molecular origins and evolution of blood, bladder, breast, and colon cancers. Scroll down. companion animals, Wed., March 20, 5:15-6:30pm, Vet School, Classroom 6 A small but significant metabolic difference between human and mouse lung tumor cells, has been discovered by Weill Cornell Medicine researchers, explaining a discrepancy in previous study results, and pointing toward new strategies for developing cancer treatments. The center coordinates multiple research projects that together will elucidate functional links between aberrant biochemical signaling and changes in the physical microenvironment that are characteristic of metastatic cancer. National Cancer Institute (NCI) Cancer Biology He is current the Meyer Director and Professor of Cancer Biology at the Sandra and Edward Meyer Cancer Center at Weill Cornell Medicine in New York City. Wed., January 23, 5:15-6:30pm, Vet School, Classroom 6 How do you decide if a person in a difficult situation has acted criminally or not? Session Leader: Denise Lee, MD; Cayuga Medical Center The Feil BMRIs multidisciplinary faculty includes 50 members with primary appointments, and 35 with primary appointments in other departments at Weill Cornell Medicine, including Neurology, Biochemistry, Anesthesiology, Pharmacology, Physiology and Biophysics, Psychiatry, Medicine, Pathology and Laboratory Medicine, Radiology, Pediatrics, and Neurological Surgery. Its goals are to promote the informed use of survey research and public opinion information, maintain and constantly enlarge a web-based library of survey research and public opinion data, develop access tools for researchers, increase international understanding, and promote cross-national research on political and social issues. The Sprecher Institute for Comparative Cancer Research identifies and develops new discoveries for clinical application, provide treatment for animals with cancer, and produce educational materials about cancer and our environment for professional and non-professional audiences. The inner lining of each sac produces a substance (or discharge) that is released through a small opening near the anal opening. 2011 Comparative Cancer Biology Program Five teams led by Weill Cornell Medicine scientists have been awarded funding from the Starr Cancer Consortium in its 16th annual grant competition. Cornell Research and Innovation moves quickly. Colorectal Cancer, Wed., March 27, 5:15-6:30pm, Vet School, Classroom 6 Session Leader: Cory Foster, MD; Cayuga Medical Center Vera Gorbunova, PhD James Amatruda, MD, PhD 2011 Comparative Cancer Biology Program. T2006 Veterinary Research Tower, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853-6401. Cornell Chronicle, Candid conversation: Cancer patients and survivors connect with Cornell students, 2 the Outdoors: Canine cancer research at Cornell University, How dogs are teaching researchers new tricks for treating cancer, The Danko Lab develops a new tool to study the genetic "switches" of tumor growth, Cornell faculty and trainees participate in the Biden Community Cancer Summit, Dr. Scott Coonrod receives Peter T. Rowley Breast Cancer Scientific Research Projects Grant from the Department of Health, Dr. Kristy Richards and colleagues receive an NIH grant to investigate cancer immunotherapy for the treatment of canine lymphoma, Dr. Andrew Whites group publishes a new study on how UV light contributes to melanoma, Profile of the Richards lab in a new article on 'Immunotherapy, Improving the Odds', Cornell scientist Dr. Michael Lukey awarded a research grant from the Breast Cancer Coalition of Rochester, Grad Student Honored for Teaching, Cancer Patient Program, 'Radical collaboration' sets its sights on cancer treatment, Kristy Richards profiled in Ezra magazine, Cornell researchers participate in Ithaca Cancer Moonshot Summit T2006 Veterinary Research Tower, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853-6401. canceratcornelltrainees-l-request@cornell.edu. Session Leader: Bruce Lewenstein, PhD; Dept of Communication, Cornell Keep up with our monthly newsletter. The center helps scholars translate their knowledge into programs, evaluate those programs, and loop the knowledge back to their research. The Chromatin Remodeling Component Arid1a Is a Suppressor of Spontaneous Mammary Tumors in Mice. The Ithaca Voice, Cornell Cancer Researchers Listen To Patients' Stories The center has been a resource for countless books, articles, and media stories. Lead Scientist 2015 - 20172 years. Cancer cells must push through physical barriers in the body in order to spread. Research Methodologies The group includes scientists from Computer Science, Engineering, Physics, and clinical investigators from Cardiology, Neurology, Radiology, and Surgery, as well as students from graduate programs form Cornell's Ithaca and Weill campuses. A veterinarian's perspective - Communicating about cancer in 2011 Comparative Cancer Biology Program Its inception brought together programs and resources previously housed in the Family Life Development Center and the Bronfenbrenner Life Course Center. Robert Weiss PhD- How to give a good presentation Session Leader: Kim Overby, MD; Cornell Graduate Certificate of Engagement in Public Communication of Science and Technology, Comparative Cancer Biology Program Faculty participate in the Meyer Cancer Center Retreat in NYC on April 7, 2017 Basic cancer research at Cornell University, and in particular, the College of Veterinary Medicine, encompasses a variety of topics that include: studies of cell cycle dynamics, receptor-linked signal transduction in normal and transformed cells, factors that influence the organ preference of metastatic tumor cells, The Sandra and Edward Meyer Cancer Center provides patients access to new cancer therapies, while training future scientists and leaders in cancer research and clinical care. 2011 Comparative Cancer Biology Program. Department of Computational Biology Seminar Series Colorectal Cancer, Wed., March 27, 5:15-6:30pm, Vet School, Classroom 6 CVM researchers studying cancer : Research being done at the College involves all aspects of cancer biology and numerous scientific approaches, including nanotechnology, stem cell research and genomics. The Sprecher Institute for Comparative Cancer Research seeks to control cancer in all species. A combined program of Weill Cornell Medical College and the Sloan-Kettering institute, we are a premiere school in Biochemical Research. Tony Bais, PhD The intention is to provide a cancer center with valuable resources for the entire Cornell research and educational environment and serves the needs of the New York state public and the Cornell veterinary medical referral community. Talented researchers and top scholars know that teaching and learning are intrinsic to one another. Cancer Research at Cornell highlighted in SCOPES Peter DelNero and Alex McGregor publish their perspectives on the Cornell-Cancer Resource Center collaboration in Science. The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy. The expectation is that research findings and new technologies developed in the study of TNBC will be applicable to other breast cancers, prostate cancer, and pancreatic cancer. To support more equitable workplaces, Michelle Duguid investigates hiring practices intended to increase diversity. Elizabeth Moore, DVM, PhD- Blog writing | Phone: (607)253-3302 The Department of Surgery represents the breadth of expertise in cancer research at Weill Cornell Medicine. Our team includes investigators focused on basic mechanisms as well as clinical outcomes. NCI Cancer Trials: Information about cancer studies, Patient Support RA Bloch Cancer Care Foundation, American College of Veterinary Internal Medicine, Cornell University College of Veterinary Medicine, Cornell Ruffian Equine Specialists, on Long Island, The Sprecher Institute for Comparative Cancer Research, NCI Cancer Trials: Information about cancer studies. SCACVIM Movie Screening Nat. Presentation and Blog Workshop Our translational and clinical researchers collaborate to convert conceptual breakthroughs into novel therapies that will benefit our patients. Read more about our programs of study. There are major strengths in leukemia as well as solid tumors (breast, gonadal, thyroid, pancreas). Cornell University Research Excellence Scholars (CURES) Resource Support for PI Research while Postdocs and Research Associates are on Parental Leave Event GrantForward Webinar for Researchers Event WEBINAR: Setting up tailored funding searches using GrantForward Resource Research Funding Announcement Digests Resource Federal Funding Resources By studying a patients cancer cells in engineered models of the human body and monitoring these cells using advanced imaging approaches, our center generates unprecedented insights into cancer progression and therapy response, says Fischbach-Teschl. The Chromatin Remodeling Component Arid1a Is a Suppressor of Spontaneous Mammary Tumors in Mice. Session Leader: Kelly Hume, DVM; Cornell Research Background Contact External Relationships Professor of Pathology and Laboratory Medicine , Pathology and Laboratory Medicine , Weill Cornell Medical College 2010 - Associate Professor of Pathology and Laboratory Medicine , Pathology and Laboratory Medicine , Weill Cornell Medical College 2005 - 2010 Commun. Courses for Energy include Zombies of the Anthropocene, Global Currents: (Im)mobility and Multi-Sited Ethnography, Atmospheric Pressures: Climate Imaginaries and Migration in the Caribbean, and The Energy Transition in the Nineteenth Century. Sprecher Institute for Comparative Cancer Research. Cornell University partnership with the Cancer Resource Center of the Finger Lakes For more information, see the Education page. Cancer advocacy, Wed., May 1, 5:15-6:30pm, Vet School, Classroom 6 In addition to supporting public opinion research and social science education around the world, says Peter Enns, Government, and executive director of the center, The Roper Center helps foster and support a vibrant interdisciplinary research community at Cornell, enhancing research on topics, such as health care, elections, information science, the environment, and more.. Cornell University Comparative Cancer Biology: Recent cancer research, headlines, and outreach done by CVM scientists More News The Feil Family Brain and Mind Research Institute (Feil BMRI) at Weill Cornell Medicine is an academic unit with departmental privileges dedicated to improving pathogenic mechanisms, diagnosis, and treatment of brain disorders. Cornell Chronicle: Daily news from Cornell University. We foster a community of renowned scholars that spans disciplines, locations, and industries in order to convert promising ideas and innovations into results that truly matter. Conducted a research project on the cell signaling pathways . 1300 York Ave. New York, NY 10065 Administration (646) 962-6132 Patient services: (646) 962-2800 It allows the public to access tens of thousands of survey questions from 1935 to the present, related to the publics values, beliefs, experiences, and attitudes about heath and what influences health. Microcalcification 'fingerprints' can yield info about cancer. Research, life-changing experiences, and community engagement are hallmarks of a Cornell undergraduate education. Patients get personalized attention, with the best available evaluation and treatment programs, including access to precision medicine advances and immune-based therapies, as well as nutrition, pain September 2016, HUS1 regulates in vivo responses to genotoxic chemotherapies. Cornell and National Park Service researchers have pinpointed the exact location of a Tlingit fort in Sitka, Alaska used in 1804 to defend against Russian colonization forces. Wnt and the Immune System in Canine Osteosarcoma, Monday, April 15, 11am, Weill Hall 226 Cancer Research. Bob Riter- Communicating with cancer patients/survivorsSpeed dating exercise to introduce students and community members, Wed., January 30, 5:15-6:30pm, Vet School, Classroom 6 APPLY NOW The Graduate Program in Pharmacology The credit goes to our faculty whose dedication to scientific discovery and commitment to improving human health have put our department on the map. Lead Scientist Advocacy: The Patient Voice in Cancer Research A presentation by Carole Baas to Community-based cancer research presentations and discussions (BIOMS 5665) at Cornell University; Cancer Research Advocacy A presentation by Jane Perlmutter to the Bladder Cancer Advocacy Network; Connecting Researchers and Patients: Practical First Steps Each year the Society chooses a theme to instigate creative approaches to matters of urgent concern. FACULTY: Send an email to canceratcornell-l-request@cornell.edu with "join" as the subject. Cornell is training a next generation of solutions-oriented scholars and scientists to meet the urgent challenges facing our world today. Breast Cancer, Wed., February 20, 5:15-6:30pm, Vet School, Classroom 6 The center's initial focus is on triple negative breast cancer (TNBC). Pathology & Immunology Martha Holden, a senior extension associate and project director in the College of Human Ecology, leads the project. Exploring and Exploiting the SpatialConstraints of Cell Signaling, Tuesday, March 26, 4pm, Vet Research Tower LH3 Cancer Genetics and Epigenetics, Experimental Therapeutics The Sandra and Edward Meyer Cancer Center provides patients access to new cancer therapies, while training future scientists and leaders in cancer research and clinical care. The Cornell Center on the Physics of Cancer Metabolism is a multi-institutional effort to better understand the mechanisms underlying metastatic cancers and ultimately explore this understanding toward more effective treatments. Commun. We are also extremely grateful to the Feil family, whose vision and generosity enabled the establishment of the Feil BMRI, and to theWeill Cornell Medicine leadership for their continued support and encouragement.. | Phone: (607)253-3302 Host/microbe relationships andcontrol of intestinal stem cell behavior in homeostasis and disease -, Signal transduction growth factor receptors; protein structure; drug design and chemical biology; signaling cues that direct cell proliferation, differentiation and development -, Etiology of spontaneous birth defects in mammals; mechanisms of meiotic recombination; DNA repair proteins in meiosis and recombination; germ cell development; ovarian development -, Pharmacology; cancer cell biology; small GTPase regulation of intracellular traffic and cellular growth control -, Reproductive physiology; molecular and cellular physiology; epigenetic reprogramming during the egg-to-embryo transition; mechanisms by which specific histone modifications are dynamically regulated during hormone-dependent gene transcription in breast cancer cells, Metalloenzyme structure and catalysis; protein electron transfer; nitric oxide enzymology; bacterial chemotaxis; circadian clock photo sensors -, Medical geneticsand genomics andcancer biology research, Molecular biotechnology; protein biogenesis and folding pathways; protein engineering -, Mechanisms of infectious diseases with particular emphasis on molecular mechanisms of bacterial infections in animal models of human diseases; host-pathogen relationships, hereditary diseases in dogs to identify genetic variants contributing to disease development -, Tissue-engineered model systems for analysis of microenvironmental conditions fundamental to cancer pathogenesis and therapy -, My research interests include creating systems to evaluate and improve the welfare of research animals, and the development and refinement of animal models of human disease, (a) Immunology of nanomaterials and implantable materials and (b) safe and targeted delivery of mRNAs and DNAs for cancer immunotherapies/vaccines andneurological diseases, Tissue morphogenesis; cell shape and architecture; organ development; gut morphogenesis; mammary gland biology; breast cancer -, Cellular biomechanics; mechanotransduction;cell migration; muscular dystrophy and cancer cell biology -, The laboratory is currently focused on further advancing the novel 3D organ-on-chip systems, as well as developing both cellular and molecular tools and in vivo models, to better understand the mechanisms through which cells regulate their response to biological and mechanical cues -, Understanding innate immunity from the receptors that detect microbes to how innate immune cells react to changes in their environment during inflammatory processes -, Regulation of cell signaling by protein lipidation, Use of contemporary methods to explore lymphocyte function in spontaneous veterinary disease, Stem cells and cancer; pathogenesis of ovarian and prostate cancers; modeling of human disease in genetically modified mice and human organoids -, Ion channel receptor/ligand interactions; NMR and molecular dynamics; molecular neurobiology and biophysics; neurotransmitter receptors and signal transduction, membrane protein traffickingandquality control mechanisms -, Role of cellular protein, lipids, and glycans play in viral infection, Genetics of reproduction and germ cell development; cancer genetics; meiosis; DNA repair; genome manipulation in mice; functional genomics -, Signaling of cellular oxidative stress; molecular mechanisms used by cellular pathways that sense and signal redox imbalances within the cell, Cell signaling and genome maintenance; DNA replication stress; phosphproteomics, Hematopoietic and hemostatic disorders in animals; mechanisms of cancer metastasis -, Basic cellular and molecular mechanisms implicated in cell fate choice and stem cell activity within tissues -, Veterinary viral pathogenesis; mesenchymal stem cell biology and regenerative medicine; mammary stem cell biology and carcinogenesis -, Molecular mechanisms for the maintenance of genomic stability; cellular responses to DNA damage; mouse models of human cancer -, Cancer biology; stem cell biology; biochemistry and cell biology -, Leukemia; cell growth and differentiation; oncogenes/genetics -.

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